About ALS
Amyotrophic lateral sclerosis (ALS) is a relentless and progressive neurodegenerative disease that affects the motor neurons of the brain and spinal cord. While symptoms vary from person to person, all forms ultimately lead to loss of independence and a markedly shortened lifespan.
About AP-101
AP-101 is a recombinant human antibody designed to selectively deplete toxic, misfolded forms of SOD1 while preserving the protective function of physiological SOD1. By targeting only the pathological conformations, AP-101 aims to disrupt a key driver of ALS progression without lowering total SOD1 levels.
