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AL-S Pharma was founded in 2016 by TVM Capital Life Science and Neurimmune to develop AP-101 for the treatment of ALS

AP-101 was originally discovered using Neurimmune’s Reverse Translational Medicine platform — a clinically validated technology for generating human antibodies that target misfolded proteins implicated in neurodegenerative diseases.

Today, AL-S Pharma brings together a seasoned team of biotech and pharmaceutical leaders with expertise spanning drug discovery, translational research, and clinical development. Based on the successful Phase 2 data, the company is now advancing AP-101 into Phase 3 and preparing for late-stage development with the goal of delivering a meaningful disease-modifying therapy for ALS.

Team


Harry Welten
Chief Executive Officer
Angela Genge, MD
Chief Medical Officer
Dirk Schimkat, lic.rer.pol
Chief Financial Officer
Bryan Boggs, Pharm.D.
Regulatory Affairs
Emma Bowden, PhD
SVP Clinical Development
Christian Somandin, PhD
CMC

Board of Directors


Hubert Birner, PhD, MBA
TVM Capital
Marc Rivière, MD
TVM Capital
Prof. Guy Rouleau, MD
Mc Gill

«I was drawn to AL-S Pharma by the scientific rigor and patient-centered mission driving the development of AP-101. Targeting misfolded SOD1 offers a promising and differentiated path in ALS, and I’m proud to help lead its clinical advancement on behalf of people living with ALS.»

Angela Genge, MD
Chief Medical Officer

«ALS remains a devastating disease with an urgent need for effective new treatment options. At AL-S Pharma, our focus is on advancing science that can translate into meaningful benefits for people living with ALS and their families. AP-101 reflects that commitment and the ambition to develop a therapy that can make a real difference in this disease.»

Harry Welten
Chief Executive Officer